¿Can Botulinum toxin affect the brain and its emotions?

Botulinum toxin, known for its aesthetic applications, is emerging as a modulator of mood through its effects on facial musculature and feedback mechanisms. Its ability to influence mood extends beyond aesthetic improvement, offering potential therapeutic benefits in emotional regulation.

Botulinum toxin induces muscle relaxation, preventing specific muscle contraction and thereby disrupting feedback loops or signals that reinforce mood to the brain (cerebral amygdala), which can potentially enhance positive emotions and promote overall wellbeing. Some studies have shown it can reduce symptoms of depression and anxiety, strengthen overall emotional resilience, enhance social interactions, increase positive emotional contagion, and contribute to a more positive self-perception. Therefore, we can go back to a popular motivational phrase that says , "If you look good, you feel good, if you feel good, you do good"

Fuente:
The Face of Emotion: Botulinum Toxin, Emotional Anatomy, and Mood Modulation